TA4. Terapia puls cu Orungal in onicomicoze non-dermatofitice
Codruta Micin, V. Feier, C. Solovan, Daniela Tulhina, Persa Ghitulescu
Timisoara

Onicomicoza poate fi cauzata de dermatofiti, nondermatofiti si levuri (candida).

Non-dermatofitii (ex. Scapulariopsis, Scytalidium Aspergillus, Fusarium) afecteaza predominant unghia de la picior si reprezinta aproximativ 3-5% din onicomicozele de la picior.

In clinica de Dermato-venerologie Timisoara, incidenta onicomicozelor ca non-dermatofiti inregistrata in 1998 a fost de 3,6%. La examenul micologic am pus in evidenta Aspergillus spp, Fusarium ssp si Scapulariopsis brevicaulis. Rata vindecarilor clinice si micologice cu itraconazol administrat in terapia puls (2-4 pulsuri) pentru onicomicozele non-dermatofitice a fost de 83%.

Rata mare a vindecarilor, complianta crescuta din partea pacientului, risc hepatic foarte redus, impun itraconazolul ca prima optiune in onicomicozele non-dermatofitice.

TA4. Puls Therapy with Itraconazole in Non-dermatophyts Onychomycosis
Codruta Micin, V. Feier, C. Solovan, Daniela Tulhina, Persa Ghitulescu
Timisoara

The onychomycosis may be caused by dermatophyts non-dermatophyts and yeasts (candida). The non-dermatophyts
(ex. Scapulariopsis, Scytalidium, Aspergillus spp, Fusarium) mostly affects the nail from the foot and represents approximatively 3-5 from the onychomycosis from the foot.

In the Dermato-Venereology Health Centre from Timisoara, the incidence of the onychomycosis with the non-dermatophyts registered in 1998 was in percent of 3.6%. At the mycologic examination we emphasize Aspergillus spp, Fusarium spp. and Scapulariopsis brevicaulis. The percent of clinical and mycological cure with Itraconazol administrated in the pulse therapy
(2-4 pulses) for the non-dermatophytic onycomycosis was 83%. the big percent of cures, the increased compliance of the patient, very low risk, impose the Itraconazol as first option in the non-dermatophyts onychomycosis.