Herpes Gestationes este o maladie buloasa cu polimorfism lezional care poate debuta atat la primipare cat si la multipare, mai frecvent in ultimele doua trimestre de sarcina.

Leziunile constau din placi eritemato-edemoase cu bule mari, in tensiune, ce afecteaza trunchiul (mai ales zona periombilicala) si membrele si se asociaza cu prurit, senzatii suparatoare de usturime sau arsura si uneori cu subfebrilitati.

Autorii prezinta cazul unei paciente primipare de 23 de ani, gravida in luna a V-a, a carei simptomatologie clinica, examen histopatologic si imunohistopatologic permite incadrarea acesteia in diagnosticul sus amintit.

Examenul ginecologic clinic si ecografic au relevat o hipotrofie fetala cu risc de mortinatalitate.

Autorii discuta riscurile teoretice ale unei atare situatii si posibilitatile terapeutice si evolutive.

Concluzia este ca, desi herpes gestationes considerata o afectiune rara (1 la 50 000 de cazuri) trebuie cunoscuta iar aprecierea prognosticului fetal este discutabila de la caz la caz.

It is a bullous malady with lesional polymorphism which can start both in primiparous and in multiparous females more frequent during the last two trimesters of pregnancy. Lesions consists of eritemato- edematous plaques with large in tension bullae placed on the trunk (especially the periumbilical area) and limbs they associated to prurit, ashing and smarting pain sensation and sometimes to subfebrility.

The authors pressent a 23 years old primiparous, in the fifth month of pregnancy woman whose clinic symptomatholgy, histopathologic and immunohistopathologic exams allow us to diagnose as herpes gestationes. Clinic and echografic gynecologic exams revealed a fetal hipotrophy with mortinatality risk.

The authors debate upon the theoretic risk of such a situation and the therapeutic and evolutive possibilities.

As a conclusion we may state that though herpes gestationes is considered a rare disease it should be known and to appreciate the fetal prognostic is different from case to case.