Sclerodermia este o boala de origine necunoscuta, prbabil produsa prin mecanisme autoimune.

Prezentam 3 cazuri de sclerodermie aparuta la copii in varsta de 8, 9 si 14 ani:

- un baiat de 14 ani cu placarde pe coapsa stanga, eritemato'violacee, discret infiltrate;

- un copil de 9 ani cu 3 placi ivorii, discret infiltrate, fara lilaciring, pe abdomen si baza toracelui;

- Un baiat de 8 ani cu placarde scleroatrofice, rapid extensive in suprafata si profunzime, la nivelul gambelor, abdomenului inferior, toracelui, cu tendinta la sterodactilie, fara fenomen Raynaud si cu leziuni de "white spot disease" pe toracele posterior.

Toate cazurile au fost confirmate histopatologic. Imunologic, nu s-au evidentiat anticorpi antivas, anti-muschi sau celule LE. Imunofluorescenta pentru Borellia a fost pozitiva la 1 caz.

Terapia a fost cortizonica, adaugandu-se pentrixifilin si vitamine, in toate cazurile. La unul din cazuri s-au adaugat
D-pencicilamina si terapie prin acupunctura, iar altul - Extencilline sau Retarpen.

Scleroderma is a disease of unknown causes. It is probably produced by autoimmunological mechanisms.

We describe 3 cases of scleroderma in children. The disease occured at ages 8, 9 and respectively 14 years:

- A 14 years old boy with erythematous, slightly infiltrated plaques on his left thigh;

- A 9 years old child with 3 ivory, slightly infiltrated plaques, without the lilac ring, on the abdomen and lower part of the chest;

- A 8 years old boy with scleroatrophic and spreading in surface and depht plaques on legs, lower abdomen and chest.
A tendency to sclerodactyly can be observed, without Reynaud's phenomenon, and also with lesions of withe spot disease on the posterior aspect of the chest.

All cases were histopatologically confirmed. Immunological investigations didn't show antivessel or antimuscle ntibodies, or LE cells. The immunofluorescence techniques for Borellia burgdorferi were positive in one of the cases.

We use in all cases systemic corticosteroids, pentoxiphilin and vitamines. Besides the above mentioned, the patients were treated - in one case using D-Penicillamine and accupuncture techniques - and in another one - Extencilline or Retarpen.